Self-Powered Wireless Affinity-Based Biosensor Based on Integration of Paper-Based Microfluidics and Self-Assembled RFID Antennas.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Author(s): Yuan M; Alocilja EC; Chakrabartty S
  • Source:
    IEEE transactions on biomedical circuits and systems [IEEE Trans Biomed Circuits Syst] 2016 Aug; Vol. 10 (4), pp. 799-806. Date of Electronic Publication: 2016 May 17.
  • Publication Type:
    Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: IEEE Country of Publication: United States NLM ID: 101312520 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1940-9990 (Electronic) Linking ISSN: 19324545 NLM ISO Abbreviation: IEEE Trans Biomed Circuits Syst Subsets: MEDLINE
    • Publication Information:
      Original Publication: New York, NY : IEEE, c2007-
    • Subject Terms:
      Microfluidics* ; Paper* ; Radio Frequency Identification Device* ; Wireless Technology*; Biosensing Techniques/*methods; Antibodies, Immobilized/chemistry ; Antibodies, Immobilized/immunology ; Antigens/analysis ; Antigens/immunology ; Biosensing Techniques/instrumentation ; Food Quality ; Gold/chemistry ; Metal Nanoparticles/chemistry
    • Abstract:
      This paper presents a wireless, self-powered, affinity-based biosensor based on the integration of paper-based microfluidics with our previously reported method for self-assembling radio-frequency (RF) antennas. At the core of the proposed approach is a silver-enhancement technique that grows portions of a RF antenna in regions where target antigens hybridize with target specific affinity probes. The hybridization regions are defined by a network of nitrocellulose based microfluidic channels which implement a self-powered approach to sample the reagent and control its flow and mixing. The integration substrate for the biosensor has been constructed using polyethylene and the patterning of the antenna on the substrate has been achieved using a low-cost ink-jet printing technique. The substrate has been integrated with passive radio-frequency identification (RFID) tags to demonstrate that the resulting sensor-tag can be used for continuous monitoring in a food supply-chain where direct measurement of analytes is typically considered to be impractical. We validate the proof-of-concept operation of the proposed sensor-tag using IgG as a model analyte and using a 915 MHz Ultra-high-frequency (UHF) RFID tagging technology.
    • Accession Number:
      0 (Antibodies, Immobilized)
      0 (Antigens)
      7440-57-5 (Gold)
    • Publication Date:
      Date Created: 20160524 Date Completed: 20171025 Latest Revision: 20171208
    • Publication Date:
      20240829
    • Accession Number:
      10.1109/TBCAS.2016.2535245
    • Accession Number:
      27214914