Scarlet Fever Upsurge in England and Molecular-Genetic Analysis in North-West London, 2014.

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  • Additional Information
    • Source:
      Publisher: National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC) Country of Publication: United States NLM ID: 9508155 Publication Model: Print Cited Medium: Internet ISSN: 1080-6059 (Electronic) Linking ISSN: 10806040 NLM ISO Abbreviation: Emerg Infect Dis Subsets: MEDLINE
    • Publication Information:
      Original Publication: Atlanta, GA : National Center for Infectious Diseases, Centers for Disease Control and Prevention (CDC), [1995-
    • Subject Terms:
      Scarlet Fever/*epidemiology ; Scarlet Fever/*microbiology ; Streptococcus pyogenes/*classification ; Streptococcus pyogenes/*genetics; Antigens, Bacterial/genetics ; Antigens, Bacterial/immunology ; Genotype ; History, 21st Century ; Humans ; London/epidemiology ; Mutation ; Scarlet Fever/history ; Scarlet Fever/immunology ; Streptococcus pyogenes/drug effects ; Streptococcus pyogenes/immunology ; Superantigens/genetics ; Superantigens/immunology
    • Abstract:
      Scarlet fever notifications surged across the United Kingdom in spring 2014. Molecular epidemiologic investigation of Streptococcus pyogenes infections in North-West London highlighted increased emm4 and emm3 infections coincident with the upsurge. Unlike outbreaks in other countries, antimicrobial resistance was uncommon, highlighting an urgent need to better understand the drivers of scarlet fever activity.
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    • Grant Information:
      G0800777 United Kingdom MRC_ Medical Research Council
    • Contributed Indexing:
      Keywords: England; London; Streptococcus pyogenes; antimicrobial resistance; bacteria; genotype; notifications; respiratory infections; scarlet fever; streptococci; superantigens
    • Accession Number:
      0 (Antigens, Bacterial)
      0 (Superantigens)
    • Publication Date:
      Date Created: 20160519 Date Completed: 20180112 Latest Revision: 20220129
    • Publication Date:
      20221213
    • Accession Number:
      PMC4880090
    • Accession Number:
      10.3201/eid2206.151726
    • Accession Number:
      27192393