[Recent advances in pharmacological intervention for prediabetes].

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  • Author(s): Lan JQ; Zhu CJ
  • Source:
    Yao xue xue bao = Acta pharmaceutica Sinica [Yao Xue Xue Bao] 2015 Dec; Vol. 50 (12), pp. 1565-72.
  • Publication Type:
    Journal Article; Review
  • Language:
    Chinese
  • Additional Information
    • Source:
      Publisher: Zhongguo yao xue hui Country of Publication: China NLM ID: 21710340R Publication Model: Print Cited Medium: Print ISSN: 0513-4870 (Print) Linking ISSN: 05134870 NLM ISO Abbreviation: Yao Xue Xue Bao Subsets: MEDLINE
    • Publication Information:
      Original Publication: Beijing : Zhongguo yao xue hui
    • Subject Terms:
      Glucose Intolerance*; Diabetes Mellitus, Type 2/*prevention & control ; Prediabetic State/*drug therapy; Animals ; Disease Models, Animal ; Drugs, Chinese Herbal/therapeutic use ; Humans
    • Abstract:
      Prediabetes is an abnormal condition between normal glucose metabolism and diabetes mellitus. Impaired glucose tolerance (IGT) is an indicator of high-risk state of prediabetes. Positive interventions of IGT, including life style changes and pharmacological intervention, can effectively postpone and reduce the development of prediabetes into type 2 diabetes mellitus, suggesting that IGT is a key point of diabetes prevention. Currently, pharmacological intervention for prediabetes is still at early stage. In this review, we summarizes recent clinical and preclinical studies on pharmacological intervention for prediabetes, and studies in the development of animal models with IGT and the application of new techniques. We also discuss the prospects of drugs for diabetes prevention, especially with the traditional Chinese medicine.
    • Accession Number:
      0 (Drugs, Chinese Herbal)
    • Publication Date:
      Date Created: 20160513 Date Completed: 20160526 Latest Revision: 20181202
    • Publication Date:
      20231215
    • Accession Number:
      27169278