Prevalence rate and clinical characteristics of esophageal ectopic sebaceous glands in asymptomatic health screen examinees.

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  • Additional Information
    • Source:
      Publisher: Oxford University Press Country of Publication: United States NLM ID: 8809160 Publication Model: Print Cited Medium: Internet ISSN: 1442-2050 (Electronic) Linking ISSN: 11208694 NLM ISO Abbreviation: Dis Esophagus Subsets: MEDLINE
    • Publication Information:
      Publication: 2017- : New York : Oxford University Press
      Original Publication: Milano : Masson, 1988-
    • Subject Terms:
      Asymptomatic Diseases* ; Sebaceous Glands*; Choristoma/*epidemiology ; Esophageal Diseases/*epidemiology ; Esophagus/*pathology; Adult ; Choristoma/pathology ; Endoscopy, Digestive System ; Esophageal Diseases/pathology ; Esophageal Neoplasms/epidemiology ; Esophagitis/epidemiology ; Female ; Humans ; Male ; Middle Aged ; Papilloma/epidemiology ; Polyps/epidemiology ; Prevalence ; Prospective Studies ; Republic of Korea/epidemiology
    • Abstract:
      Ectopic sebaceous glands in the esophagus have rarely been reported and, thus, represent an obscure medical condition. The aim of this study is to identify the prevalence rate and clinical characteristics of this lesion in an asymptomatic population. We prospectively enrolled health screen examinees who underwent esophagogastroduodenoscopy for gastric cancer screening. An esophageal biopsy was performed in the cases in which esophageal ectopic sebaceous glands were suspected. The general characteristics of the examinees were analyzed based on their medical records. A total of 9989 examinees were enrolled, and five examinees were diagnosed with esophageal ectopic sebaceous glands between December 2012 and June 2014. The endoscopic findings of the esophageal ectopic sebaceous glands indicated multiple yellowish patches or papules, which varied in size. The histopathological findings indicated several lobulated sebaceous glands in the squamous epithelium with inflammatory infiltration. The follow-up endoscopic findings indicated that there was no grossly discernible change. In conclusion, esophageal ectopic sebaceous glands are present in 0.05% of asymptomatic subjects. This lesion is thought to be benign and is not related to clinical symptoms. Therefore, esophageal ectopic sebaceous glands do not require further treatment or follow-up, which makes endoscopists free from active efforts for differential diagnosis with other malignant diseases.
      (© 2016 International Society for Diseases of the Esophagus.)
    • Contributed Indexing:
      Keywords: endoscopy; esophagus; sebaceous glands
    • Publication Date:
      Date Created: 20160130 Date Completed: 20171016 Latest Revision: 20171016
    • Publication Date:
      20240829
    • Accession Number:
      10.1111/dote.12453
    • Accession Number:
      26822541