Encapsulating peritoneal sclerosis: surgery, sustained drug therapy and treatment of recurrence at 1 year.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Author(s): Cho R;Cho R; Ghag D; Ghag D; Karim MA; Karim MA; Lo C; Lo C
  • Source:
    BMJ case reports [BMJ Case Rep] 2015 Nov 11; Vol. 2015. Date of Electronic Publication: 2015 Nov 11.
  • Publication Type:
    Case Reports; Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BMJ Pub. Group
    • Subject Terms:
      Kidney Failure, Chronic/*therapy ; Peritoneal Dialysis, Continuous Ambulatory/*methods ; Peritoneal Fibrosis/*diagnosis; Aged ; Anti-Inflammatory Agents/therapeutic use ; Female ; Humans ; Immunosuppressive Agents/therapeutic use ; Nausea/etiology ; Peritoneal Fibrosis/drug therapy ; Prednisone/therapeutic use ; Tamoxifen/therapeutic use ; Tomography, X-Ray Computed ; Treatment Outcome ; Vomiting/etiology
    • Abstract:
      A 74-year-old woman with end-stage renal disease presented with clinical symptoms of encapsulating peritoneal sclerosis 2 years after switching from peritoneal dialysis to haemodialysis. Imaging revealed a large cystic structure in her abdomen and her final diagnosis was made by exploratory laparotomy. A 10 cm×15 cm fibrous rind was excised from the peritoneum and the patient was subsequently started on tamoxifen 20 mg daily and prednisone 20 mg daily. Given her reduction in clinical symptoms and concerns about the long-term effects of corticosteroids, prednisone was tapered and she remained on tamoxifen monotherapy. 1 year postsurgery, she presented with symptoms of nausea, vomiting and anorexia. A repeat CT of the abdomen confirmed a recurrence of encapsulating peritoneal sclerosis. Prednisone and tamoxifen were restarted at increased dosages of 25 and 40 mg daily, respectively. The patient's symptoms were ameliorated within 2 weeks of drug therapy modification.
      (2015 BMJ Publishing Group Ltd.)
    • References:
      Clin J Am Soc Nephrol. 2008 Nov;3(6):1702-10. (PMID: 18667742)
      Saudi J Kidney Dis Transpl. 2013 Mar;24(2):223-9. (PMID: 23538342)
      Nephrol Dial Transplant. 2013 Apr;28(4):1021-30. (PMID: 22734107)
      Perit Dial Int. 2005 Apr;25 Suppl 4:S83-95. (PMID: 16300277)
      Perit Dial Int. 2005 Apr;25 Suppl 4:S39-47. (PMID: 16300271)
      Perit Dial Int. 2011 May-Jun;31(3):291-300. (PMID: 21454390)
      Nephrol Dial Transplant. 2011 Feb;26(2):691-7. (PMID: 20584735)
      Adv Perit Dial. 2006;22:60-4. (PMID: 16983941)
      Am J Kidney Dis. 2004 Oct;44(4):729-37. (PMID: 15384025)
      Perit Dial Int. 2013 Sep-Oct;33(5):495-502. (PMID: 23378473)
      Perit Dial Int. 2005 Apr;25 Suppl 4:S30-8. (PMID: 16300270)
      Nat Rev Nephrol. 2011 Aug 02;7(9):528-38. (PMID: 21808281)
      Nephrol Dial Transplant. 2009 Oct;24(10):3209-15. (PMID: 19211652)
      Neth J Med. 2011 Nov-Dec;69(11):500-7. (PMID: 22173363)
    • Accession Number:
      0 (Anti-Inflammatory Agents)
      0 (Immunosuppressive Agents)
      094ZI81Y45 (Tamoxifen)
      VB0R961HZT (Prednisone)
    • Publication Date:
      Date Created: 20151113 Date Completed: 20160913 Latest Revision: 20181113
    • Publication Date:
      20221213
    • Accession Number:
      PMC4654214
    • Accession Number:
      10.1136/bcr-2015-211490
    • Accession Number:
      26561223