High-density interspecific genetic linkage mapping provides insights into genomic incompatibility between channel catfish and blue catfish.

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  • Additional Information
    • Source:
      Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 8605704 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2052 (Electronic) Linking ISSN: 02689146 NLM ISO Abbreviation: Anim Genet Subsets: MEDLINE
    • Publication Information:
      Publication: Oxford, England : Wiley-Blackwell
      Original Publication: Oxford, England : Published by Blackwell Scientific Publications for the International Society for Animal Blood Group Research, c1986-
    • Subject Terms:
      Chromosome Mapping* ; Genetic Linkage* ; Polymorphism, Single Nucleotide*; Ictaluridae/*genetics; Animals ; Female ; Gene Rearrangement ; Genetic Markers ; Ictaluridae/classification ; Male
    • Abstract:
      Catfish is the leading aquaculture species in the United States. The interspecific hybrid catfish produced by mating female channel catfish with male blue catfish outperform both of their parent species in a number of traits. However, mass production of the hybrids has been difficult because of reproductive isolation. Investigations of genome structure and organization of the hybrids provide insights into the genetic basis for maintenance of species divergence in the face of gene flow, thereby helping develop strategies for introgression and efficient production of the hybrids for aquaculture. In this study, we constructed a high-density genetic linkage map using the hybrid catfish system with the catfish 250K SNP array. A total of 26,238 SNPs were mapped to 29 linkage groups, with 12,776 unique marker positions. The linkage map spans approximately 3240 cM with an average intermarker distance of 0.25 cM. A fraction of markers (986 of 12,776) exhibited significant deviation from the expected Mendelian ratio of segregation, and they were clustered in major genomic blocks across 15 LGs, most notably LG9 and LG15. The distorted markers exhibited significant bias for maternal alleles among the backcross progenies, suggesting strong selection against the blue catfish alleles. The clustering of distorted markers within genomic blocks should lend insights into speciation as marked by incompatibilities between the two species. Such findings should also have profound implications for understanding the genomic evolution of closely related species as well as the introgression of hybrid production programs in aquaculture.
      (© 2015 Stichting International Foundation for Animal Genetics.)
    • Contributed Indexing:
      Keywords: Interspecific crossing; hybrid catfish; hybrid incompatibility; segregation distortion; single nucleotide polymorphism
    • Accession Number:
      0 (Genetic Markers)
    • Publication Date:
      Date Created: 20151106 Date Completed: 20160518 Latest Revision: 20220408
    • Publication Date:
      20240829
    • Accession Number:
      10.1111/age.12372
    • Accession Number:
      26537786