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Antibiotic Resistance of Campylobacter jejuni and C. coli Isolated from Children with Diarrhea in Thailand and Japan.
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- Additional Information
- Source:
Publisher: National Institute of Infectious Diseases Country of Publication: Japan NLM ID: 100893704 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1884-2836 (Electronic) Linking ISSN: 13446304 NLM ISO Abbreviation: Jpn J Infect Dis Subsets: MEDLINE
- Publication Information:
Original Publication: Tokyo, Japan : National Institute of Infectious Diseases, [1999-
- Subject Terms:
- Abstract:
A total of 29 Campylobacter jejuni and C. coli strains were isolated from Thai and Japanese children with diarrhea using the Loop-mediated Isothermal Amplification method. The samples were evaluated for mutations in gyrA and 23S rRNA in order to assess resistance against fluoroquinolones and macrolides, respectively. Among the isolated strains, 9 (8 C. jejuni and 1 C. coli) were from Thai children, and the other 20 (C. jejuni) were isolated from Japanese children. High fluoroquinolone resistance rates were observed in Thai (66.7%) and Japanese (90%) children. Macrolide resistance was not observed in Japanese children but was observed at a considerable rate of 12.5% of C. jejuni isolated in the Thai cohort. The results indicate that continuous monitoring of resistance of Campylobacter strains to fluoroquinolones and macrolides is definitely necessary.
- Accession Number:
0 (Anti-Bacterial Agents)
0 (Fluoroquinolones)
0 (Macrolides)
0 (RNA, Ribosomal, 23S)
EC 5.99.1.3 (DNA Gyrase)
- Publication Date:
Date Created: 20150714 Date Completed: 20161018 Latest Revision: 20201209
- Publication Date:
20221213
- Accession Number:
10.7883/yoken.JJID.2014.582
- Accession Number:
26166497
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