[The French National Compound Library: advances and future prospects].

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  • Author(s): Mahuteau-Betzer F;Mahuteau-Betzer F
  • Source:
    Medecine sciences : M/S [Med Sci (Paris)] 2015 Apr; Vol. 31 (4), pp. 417-22. Date of Electronic Publication: 2015 May 08.
  • Publication Type:
    English Abstract; Journal Article; Review
  • Language:
    French
  • Additional Information
    • Transliterated Title:
      Chimiothèque Nationale - Avancées et perspectives.
    • Source:
      Publisher: EDK Country of Publication: France NLM ID: 8710980 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0767-0974 (Print) Linking ISSN: 07670974 NLM ISO Abbreviation: Med Sci (Paris) Subsets: MEDLINE
    • Publication Information:
      Publication: <2003->: Paris : EDK
      Original Publication: [Paris] : Flammarion, [1985-
    • Subject Terms:
      Small Molecule Libraries*/supply & distribution; Databases, Chemical/standards ; Databases, Chemical/supply & distribution ; Databases, Chemical/trends ; Drug Evaluation, Preclinical ; Drug Information Services/standards ; Drug Information Services/supply & distribution ; Drug Information Services/trends ; France ; Humans ; Information Dissemination ; Molecular Conformation
    • Abstract:
      The French National Compound Library (Chimiothèque Nationale) has been created in 2003 and is the federation of local collections. It contains more than 56 000 small molecules and natural compounds synthesised or isolated in different laboratories over the past years. This explains the diversity of the collection. The strength of this initiative is the ability to connect chemists and biologists for the development of hits. This development involves the synthesis of analogues or/and chemical tools to find new targets. These collaborations lead to the identification of new chemical probes. These probes able to modulate a biological function are essential to study biological pathways. They can also be useful for therapeutic applications. This article will describe the major achievements and perspectives of the French Chemical Library.
      (© 2015 médecine/sciences – Inserm.)
    • Accession Number:
      0 (Small Molecule Libraries)
    • Publication Date:
      Date Created: 20150512 Date Completed: 20150810 Latest Revision: 20150511
    • Publication Date:
      20240829
    • Accession Number:
      10.1051/medsci/20153104016
    • Accession Number:
      25958760