Item request has been placed!
×
Item request cannot be made.
×
Processing Request
Endothelin stimulates release of atrial natriuretic peptides in vitro and in vivo.
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
- Additional Information
- Source:
Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0375521 Publication Model: Print Cited Medium: Print ISSN: 0024-3205 (Print) Linking ISSN: 00243205 NLM ISO Abbreviation: Life Sci Subsets: MEDLINE
- Publication Information:
Publication: <2008->: Amsterdam : Elsevier
Original Publication: Oxford; Elmsford, N. Y. [etc.] Pergamon Press.
- Subject Terms:
- Abstract:
The effect of endothelin (END) on the release of atrial natriuretic peptides (ANP) was studied in isolated rat atria and in conscious rats. END stimulates the ANP release in vitro in a dose-dependent manner. An increase in ANP plasma levels and cyclic GMP plasma levels was also observed in conscious rats after injection of END. When a monoclonal antibody directed against ANP was injected together with END the increase in cyclic GMP was completely blocked. From this study it is concluded that END is a potent secretagogue for ANP both in vitro and in vivo.
- Accession Number:
0 (Antibodies, Monoclonal)
0 (Endothelins)
0 (Peptides)
0 (Vasoconstrictor Agents)
85637-73-6 (Atrial Natriuretic Factor)
H2D2X058MU (Cyclic GMP)
- Publication Date:
Date Created: 19890101 Date Completed: 19891031 Latest Revision: 20190701
- Publication Date:
20231215
- Accession Number:
10.1016/0024-3205(89)90200-2
- Accession Number:
2552240
No Comments.