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[Persistant perfluorinated compounds cause immunotoxic effects].
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- Additional Information
- Transliterated Title:
Persistente fluorforbindelser reducerer immunfunktionen.
- Source:
Publisher: Den Alm Danske Laegerforening Country of Publication: Denmark NLM ID: 0141730 Publication Model: Print Cited Medium: Internet ISSN: 1603-6824 (Electronic) Linking ISSN: 00415782 NLM ISO Abbreviation: Ugeskr Laeger Subsets: MEDLINE
- Publication Information:
Original Publication: Copenhagen : Den Alm Danske Laegerforening
- Subject Terms:
- Abstract:
Perfluorinated compounds are highly stable and useful industrial chemicals. Both perfluorooctane sulfonic acid and perfluorooctanoic acid cause immunotoxic effects in animal models at serum concentrations similar to human levels. In children who have undergone routine vaccinations, serum concentrations of these substances are inversely associated with concentrations of antibodies against diphtheria and tetanus. Prevention of such effects will require a decrease of exposure limits by at least 100-fold. Immunotoxicity is not included in routine testing of industrial chemicals but urgently needs attention.
- Grant Information:
R01 ES012199 United States ES NIEHS NIH HHS
- Accession Number:
0 (Alkanesulfonic Acids)
0 (Caprylates)
0 (Diphtheria Toxoid)
0 (Diphtheria-Tetanus Vaccine)
0 (Fluorocarbons)
0 (Immunotoxins)
0 (Tetanus Toxoid)
947VD76D3L (perfluorooctanoic acid)
9H2MAI21CL (perfluorooctane sulfonic acid)
- Publication Date:
Date Created: 20141029 Date Completed: 20160929 Latest Revision: 20211021
- Publication Date:
20221213
- Accession Number:
25350410
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