Usefulness of morning home blood pressure measurements in patients with type 2 diabetes mellitus: results of a 10-year, prospective, longitudinal study.

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  • Author(s): Kamoi K;Kamoi K
  • Source:
    Clinical and experimental hypertension (New York, N.Y. : 1993) [Clin Exp Hypertens] 2015; Vol. 37 (2), pp. 122-7. Date of Electronic Publication: 2014 Apr 30.
  • Publication Type:
    Journal Article; Randomized Controlled Trial
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Informa Healthcare Country of Publication: England NLM ID: 9305929 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-6006 (Electronic) Linking ISSN: 10641963 NLM ISO Abbreviation: Clin Exp Hypertens Subsets: MEDLINE
    • Publication Information:
      Publication: London : Informa Healthcare
      Original Publication: New York, N.Y. : Marcel Dekker, Inc., c1993-
    • Subject Terms:
      Forecasting*; Blood Pressure/*physiology ; Blood Pressure Monitoring, Ambulatory/*methods ; Circadian Rhythm/*physiology ; Diabetes Mellitus, Type 2/*physiopathology ; Hypertension/*physiopathology; Adult ; Aged ; Cause of Death/trends ; Cross-Sectional Studies ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/epidemiology ; Female ; Follow-Up Studies ; Humans ; Hypertension/epidemiology ; Hypertension/etiology ; Incidence ; Japan/epidemiology ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Prospective Studies ; Risk Factors ; Survival Rate/trends ; Young Adult
    • Abstract:
      Previous cross-sectional studies and 6-year longitudinal study have demonstrated that home blood pressure (HBP) measurements upon awakening have a stronger predictive power for death, micro- and macrovascular complications than clinic blood pressure (CBP) measurements in patients with type 2 diabetes (T2DM). This study investigated which of these measurements offers stronger predictive power for outcomes over 10 years. At baseline, 400 Japanese patients with T2DM were classified as having hypertension (HT) or normotension (NT) based on HBP and CBP. The mean survey duration was 95 months. Primary and secondary end-points were death and new or worsened micro- and macrovascular complications, respectively. Differences in outcomes for each end-point between HT and NT patients were analyzed using Kaplan-Meier survival curves and log-rank testing. Associated risk factors were assessed using Cox proportional hazards analysis. Based on HBP, death and micro- and macrovascular complications were significantly higher in patients with HT than with NT at baseline and end-point. Based on CBP, there were no significant differences in incidence of death, micro- or macrovascular complications between patients with HT and NT at baseline and end-point, although a significant difference in incidence of death was observed between the HT and NT groups at end-point. However, the significance was significantly lower in CBP than in HBP. One risk factor associated with micro- and macrovascular complications in patients with HBP was therapy for HT. This 10-year longitudinal study of patients with T2DM demonstrated that elevated HBP upon awakening is predictive of death, and micro- and macrovascular complications.
    • Contributed Indexing:
      Keywords: Clinic blood pressure; clinic hypertension; home blood pressure; morning hypertension; type 2 diabetes mellitus
    • Publication Date:
      Date Created: 20140503 Date Completed: 20151203 Latest Revision: 20220408
    • Publication Date:
      20221213
    • Accession Number:
      10.3109/10641963.2014.913606
    • Accession Number:
      24786228