Dexamethasone inhibition of phagocytosis by corneal keratocytes in culture.

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  • Author(s): Mishima H;Mishima H; Nishida T; Otori T
  • Source:
    Archives of ophthalmology (Chicago, Ill. : 1960) [Arch Ophthalmol] 1988 Jul; Vol. 106 (7), pp. 978-80.
  • Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: American Medical Association Country of Publication: United States NLM ID: 7706534 Publication Model: Print Cited Medium: Print ISSN: 0003-9950 (Print) Linking ISSN: 00039950 NLM ISO Abbreviation: Arch Ophthalmol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Chicago, IL : American Medical Association
    • Subject Terms:
      Keratins*; Cornea/*cytology ; Dexamethasone/*pharmacology ; Phagocytosis/*drug effects; Animals ; Cells, Cultured ; Endothelium, Corneal/cytology ; Epithelial Cells
    • Abstract:
      To investigate the effect of steroid hormone on phagocytosis by keratocytes, we investigated the phagocytic activities for latex beads by rabbit corneal keratocytes cultured in the presence and absence of dexamethasone. Culturing the corneal keratocytes with dexamethasone inhibited the phagocytic activity for latex beads in a dose-dependent fashion. The inhibitory effects depended on the duration of the incubation period of the cells with dexamethasone.
    • Accession Number:
      68238-35-7 (Keratins)
      7S5I7G3JQL (Dexamethasone)
    • Publication Date:
      Date Created: 19880701 Date Completed: 19880804 Latest Revision: 20190704
    • Publication Date:
      20240829
    • Accession Number:
      10.1001/archopht.1988.01060140124038
    • Accession Number:
      2455497