[Characteristics of 200 patients with suspected implant allergy compared to 100 symptom-free arthroplasty patients].

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  • Additional Information
    • Transliterated Title:
      Charakteristika von 200 Patienten mit Verdacht auf Implantatallergie im Vergleich zu 100 beschwerdefreien Endoprothesenträgern.
    • Source:
      Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0331266 Publication Model: Print Cited Medium: Internet ISSN: 1433-0431 (Electronic) Linking ISSN: 00854530 NLM ISO Abbreviation: Orthopade Subsets: MEDLINE
    • Publication Information:
      Original Publication: Berlin, New York, Springer-Verlag.
    • Subject Terms:
      Bone Cements* ; Gentamicins*; Arthroplasty/*statistics & numerical data ; Hip Prosthesis/*statistics & numerical data ; Hypersensitivity/*diagnosis ; Hypersensitivity/*epidemiology ; Knee Prosthesis/*statistics & numerical data; Adult ; Arthroplasty/instrumentation ; Female ; Germany/epidemiology ; Humans ; Joint Prosthesis ; Male ; Middle Aged ; Prevalence ; Risk Factors
    • Abstract:
      Background: Data on implant allergies are incomplete; therefore, we compared the data on allergy history, patch test (PT) and lymphocyte transformation test (LTT) results in a patient series from the Munich implant allergy outpatient department with symptom-free arthroplasty patients.
      Patients and Methods: In this study 200 arthroplasty patients with complaints involving the prosthesis (130 female, 187 knee and 13 hip prostheses) and in parallel 100 symptom-free patients (75 female, 47 knee and 53 hip prostheses) were investigated. A questionnaire-aided history including implant type, cementing, intolerance of dental materials, atopy, cutaneous metal intolerance (CMI) and PT, including a standard series with Ni, Co, Cr, seven bone cement components, including gentamicin and benzoyl peroxide and LTT for Ni, Co and Cr.
      Results: In the knee arthroplasty patients with complaints 9.1% showed dental material intolerance, 23.5% atopy, 25.7% CMI, 18.2% metal allergies, 7.4% gentamicin allergy and 27.8% positive metal LTT (mostly to Ni). In symptom-free patients 0% showed dental material intolerance, 19.1% atopy, 12.8% CMI, 12.8% metal allergy, 0% gentamicin allergy and 17% positive metal LTT.
      Conclusions: Characteristics of the patients with complaints were increased intolerance of dental materials, higher rates of atopy, CMI, metal and gentamicin allergy and LTT reactivity.
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    • Accession Number:
      0 (Bone Cements)
      0 (Gentamicins)
    • Publication Date:
      Date Created: 20130803 Date Completed: 20140304 Latest Revision: 20211021
    • Publication Date:
      20221213
    • Accession Number:
      10.1007/s00132-012-2038-0
    • Accession Number:
      23907451