[Changes of intraocular cytokine level in patients with vascular and neovascular retinal pathology depending on pathologic process activity].

Publisher: Media Sfera Country of Publication: Russia (Federation) NLM ID: 0415216 Publication Model: Print Cited Medium: Print ISSN: 0042-465X (Print) Linking ISSN: 0042465X NLM ISO Abbreviation: Vestn Oftalmol Subsets: MEDLINE

Publication: Moskva : Media Sfera
Original Publication: Moskva. Meditsina.

Aqueous Humor/*metabolism ; Cytokines/*metabolism ; Retina/*pathology ; Retinal Neovascularization/*metabolism ; Retinal Vasculitis/*metabolism; Adult ; Aged ; Biomarkers/metabolism ; Disease Progression ; Female ; Fluorescein Angiography ; Fundus Oculi ; Humans ; Immunoenzyme Techniques ; Male ; Middle Aged ; Retinal Neovascularization/pathology ; Retinal Vasculitis/pathology ; Severity of Illness Index ; Tomography, Optical Coherence

Cytokine and growth factors levels were estimated in anterior chamber humor of patients with different diseases manifesting with vascular and neovascular retinal changes and various pathologic process activity. 40 patients with macula edema, retinal and choroid neovascularization were examined. Process activity was determined based on data obtained using high-resolution optical coherence tomography and fluorescent angiography. Quantitative concentration of interleukine 6, 8, vascular endothelium growth factor and monocyte chemoattractive protein-1 in anterior chamber aqueous humor was measured using enzyme immunoassay. Increased level of cytokines studied was found in all forms of the diseases.

0 (Biomarkers)
0 (Cytokines)

Date Created: 20130725 Date Completed: 20130813 Latest Revision: 20151119

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