[A case of refractory deep incisional surgical site infection due to methicillin-resistant Staphylococcus aureus (MRSA) and successfully treated with oral linezolid].

Publisher: Gan To Kagaku Ryohosha Country of Publication: Japan NLM ID: 7810034 Publication Model: Print Cited Medium: Print ISSN: 0385-0684 (Print) Linking ISSN: 03850684 NLM ISO Abbreviation: Gan To Kagaku Ryoho Subsets: MEDLINE

Publication: Tokyo : Gan To Kagaku Ryohosha
Original Publication: Tōkyō, Gan to Kagaku Ryōhōsha [1974?]-

Methicillin Resistance*; Acetamides/*therapeutic use ; Anti-Infective Agents/*therapeutic use ; Methicillin-Resistant Staphylococcus aureus/*drug effects ; Oxazolidinones/*therapeutic use ; Staphylococcal Infections/*drug therapy ; Surgical Wound Infection/*drug therapy; Acetamides/administration & dosage ; Administration, Oral ; Aged ; Anti-Infective Agents/administration & dosage ; Gastrectomy ; Humans ; Linezolid ; Male ; Oxazolidinones/administration & dosage ; Stomach Neoplasms/surgery ; Surgical Wound Infection/microbiology

We report a case of methicillin-resistant Staphylococcus aureus(MRSA) surgical site infection successfully treated with linezolid. A 66-year-old man had undergone total gastrectomy for gastric cancer after neoadjuvant chemotherapy. Three days after the operation, he was diagnosed with deep incisional surgical site infection due to MRSA, and wound care was started. After discharge, he received adjuvant chemotherapy and wound care, but the wound had not healed in 10 months. We started treatment with oral linezolid and nutritional support, and the wound was fully healed 12 months after the operation. Antibiotic treatment with oral linezolid may be effective for refractory deep incisional surgical site infection due to MRSA in outpatients.

0 (Acetamides)
0 (Anti-Infective Agents)
0 (Oxazolidinones)
ISQ9I6J12J (Linezolid)

Date Created: 20121227 Date Completed: 20130409 Latest Revision: 20151119

20221213

23268104