Biochemical mutagens affect the preservation of fungi and biodiversity estimations.

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  • Author(s): Paterson RR;Paterson RR; Lima N
  • Source:
    Applied microbiology and biotechnology [Appl Microbiol Biotechnol] 2013 Jan; Vol. 97 (1), pp. 77-85. Date of Electronic Publication: 2012 Nov 10.
  • Publication Type:
    Journal Article; Review
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Springer International Country of Publication: Germany NLM ID: 8406612 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0614 (Electronic) Linking ISSN: 01757598 NLM ISO Abbreviation: Appl Microbiol Biotechnol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Berlin ; New York : Springer International, c1984-
    • Subject Terms:
      Biodiversity* ; Mutagenesis* ; Mutation*; Fungi/*drug effects ; Fungi/*genetics ; Mutagens/*metabolism ; Preservation, Biological/*methods
    • Abstract:
      Many fungi have significant industrial applications or biosafety concerns and maintaining the original characteristics is essential. The preserved fungi have to represent the situation in nature for posterity, biodiversity estimations, and taxonomic research. However, spontaneous fungal mutations and secondary metabolites affecting producing fungi are well known. There is increasing interest in the preservation of microbes in Biological Resource Centers (BRC) to ensure that the organisms remain viable and stable genetically. It would be anathema if they contacted mutagens routinely. However, for the purpose of this discussion, there are three potential sources of biochemical mutagens when obtaining individual fungi from the environment: (a) mixtures of microorganisms are plated routinely onto growth media containing mutagenic antibiotics to control overgrowth by contaminants, (b) the microbial mixtures may contain microorganisms capable of producing mutagenic secondary metabolites, and (c) target fungi for isolation may produce "self" mutagens in pure culture. The probability that these compounds could interact with fungi undermines confidence in the preservation process and the potential effects of these biochemical mutagens are considered for the first time on strains held in BRC in this review.
    • Accession Number:
      0 (Mutagens)
    • Publication Date:
      Date Created: 20121113 Date Completed: 20130604 Latest Revision: 20130104
    • Publication Date:
      20221213
    • Accession Number:
      10.1007/s00253-012-4554-6
    • Accession Number:
      23143468