Discussion of “p-Value Calculation for Multistage Phase II Cancer Clinical Trials”.

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    • Abstract:
      The article provides the author's discussion concerning the study entitled "p-Value Calculation for Multistage Phase II Cancer Clinical Trials." He proposed that the goal of assessing the evidence regarding the null hypothesis is best achieved by using the likelihood ratio (LR) ordering rather than the UMVUE ordering proposed by authors of the study by plotting the adjusted p-values for both orderings on the y-axis.