[Ranolazine in the treatment of chronic stable angina].

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  • Additional Information
    • Transliterated Title:
      La Ranolazina nella terapia della angina cronica stabile.
    • Source:
      Publisher: Societa Editrice Universo Country of Publication: Italy NLM ID: 0372604 Publication Model: Print Cited Medium: Internet ISSN: 1972-6007 (Electronic) Linking ISSN: 00099074 NLM ISO Abbreviation: Clin Ter Subsets: MEDLINE
    • Publication Information:
      Original Publication: Roma : Societa Editrice Universo
    • Subject Terms:
      Acetanilides/*therapeutic use ; Angina, Stable/*drug therapy ; Piperazines/*therapeutic use; Acetanilides/pharmacology ; Cardiovascular System/drug effects ; Humans ; Piperazines/pharmacology ; Ranolazine
    • Abstract:
      Coronary artery disease is the leading cause of death in Europe and in the US and angina is the most common symptom associated with stable coronary artery disease. Despite receiving optimal antianginal therapy, based on agents such as beta-blockers, calcium channel antagonists and nitrates, many patients continue to experience angina. Furthermore, the administration of these drugs is limited by adverse effects such as bradycardia or hypotension. Ranolazine is a new antianginal agent, recently approved as add-on therapy in patients with stable angina. This review will focus on its mechanism of action, tolerability, highlighting the clinical benefit coming from its use.
    • Accession Number:
      0 (Acetanilides)
      0 (Piperazines)
      A6IEZ5M406 (Ranolazine)
    • Publication Date:
      Date Created: 20120912 Date Completed: 20131112 Latest Revision: 20151119
    • Publication Date:
      20240829
    • Accession Number:
      22964698