Hyperparathyroidism in a renal transplant patient: an unusual cause of resistance to therapy.

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  • Author(s): Somalanka S;Somalanka S; Phanish MK
  • Source:
    BMJ case reports [BMJ Case Rep] 2012 Aug 13; Vol. 2012. Date of Electronic Publication: 2012 Aug 13.
  • Publication Type:
    Case Reports; Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BMJ Pub. Group
    • Subject Terms:
      Bone Density Conservation Agents/*therapeutic use ; Hydroxycholecalciferols/*therapeutic use ; Hyperparathyroidism/*drug therapy ; Parathyroid Glands/*transplantation; Arm ; Drug Resistance ; Female ; Humans ; Kidney Transplantation ; Middle Aged ; Phlebotomy/methods
    • Abstract:
      A long-term renal transplant patient who was regularly followed up in the transplant clinic with stable renal allograft function was found to have elevated parathyroid hormone (PTH) levels on a biointact PTH assay. The elevated PTH levels were resistant to suppression on increasing doses of 1-alfacalcidol. Detailed history taking and clinical examination revealed the reason for apparent resistance to therapy.
    • References:
      Nephron. 2001 Jun;88(2):97-106. (PMID: 11399910)
      Transplantation. 2005 Mar 27;79(6):629-34. (PMID: 15785362)
      Ann Surg. 1984 Jul;200(1):18-23. (PMID: 6732323)
    • Accession Number:
      0 (Bone Density Conservation Agents)
      0 (Hydroxycholecalciferols)
      URQ2517572 (alfacalcidol)
    • Publication Date:
      Date Created: 20120815 Date Completed: 20140221 Latest Revision: 20211021
    • Publication Date:
      20240829
    • Accession Number:
      PMC4543690
    • Accession Number:
      10.1136/bcr-2012-006463
    • Accession Number:
      22891023