[The comparison between early enteral nutrition and total parenteral nutrition after total gastrectomy in patients with gastric cancer: the randomized prospective study].

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  • Author(s): Kim HU;Kim HU; Chung JB; Kim CB
  • Source:
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi [Korean J Gastroenterol] 2012 Jun 25; Vol. 59 (6), pp. 407-13.
  • Publication Type:
    English Abstract; Journal Article; Randomized Controlled Trial
  • Language:
    Korean
  • Additional Information
    • Source:
      Publisher: Korean Society of Gastroenterology Country of Publication: Korea (South) NLM ID: 101189416 Publication Model: Print Cited Medium: Internet ISSN: 2233-6869 (Electronic) Linking ISSN: 15989992 NLM ISO Abbreviation: Korean J Gastroenterol Subsets: MEDLINE
    • Publication Information:
      Original Publication: Seoul, Korea : Korean Society of Gastroenterology, [2003]-
    • Subject Terms:
      Enteral Nutrition* ; Parenteral Nutrition, Total*; Stomach Neoplasms/*surgery; Adult ; Aged ; Aged, 80 and over ; Alanine Transaminase/blood ; Aspartate Aminotransferases/blood ; Bilirubin/blood ; Female ; Gastrectomy ; Humans ; Length of Stay ; Male ; Middle Aged ; Postoperative Care ; Prospective Studies
    • Abstract:
      Background/aims: Early enteral nutrition (EEN) has benefits in reducing infectious complication, length of stay (LOS) and preserving liver function. There are few data about the effect of EEN in the patients who had total gastrectomy. The aim of this randomized and prospective study was to evaluate the effect of EEN after total gastrectomy on nutritional status, liver function, complications and LOS, compared to total parenteral nutrition (TPN) in patients with gastric cancer.
      Methods: Among 56 patients with gastric cancer, 36 and 20 were randomly assigned to EEN and TPN groups, and finally 17 and 16 completed EEN and TPN schedules, respectively. The nutritional parameters, liver function, LOS and abdominal symptoms were compared between 2 groups on pre-operative day and post-operative 7th day.
      Results: There was no significant difference in the nutritional parameters, liver function between EEN and TPN groups. Vomiting and abdominal distention were more frequent in EEN than TPN group (2 vs. 0 cases, p=0.485; 1 vs. 0 case, p=1.000, respectively), while increased AST, ALT and total bilirubin were more common in TPN than EEN group (4 vs. 2 cases, p=0.398; 1 vs. 0 case, p=0.485, respectively without statistical significance). LOS was shorter in EEN than TPN group without statistical significance (12 vs. 13 days, p=0.289).
      Conclusions: No significant differences were found in the nutritional status parameters, liver function, complications and LOS between EEN and TPN groups on 7th day after total gastrectomy. Further large scale studies on the advantages and disadvantages of EEN after total gastrectomy are warranted.
    • Accession Number:
      EC 2.6.1.1 (Aspartate Aminotransferases)
      EC 2.6.1.2 (Alanine Transaminase)
      RFM9X3LJ49 (Bilirubin)
    • Publication Date:
      Date Created: 20120628 Date Completed: 20121024 Latest Revision: 20191112
    • Publication Date:
      20231215
    • Accession Number:
      10.4166/kjg.2012.59.6.407
    • Accession Number:
      22735873