Menu
×
West Ashley Library
9 a.m. – 7 p.m.
Phone: (843) 766-6635
Folly Beach Library
Closed
Phone: (843) 588-2001
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Wando Mount Pleasant Library
9 a.m. – 8 p.m.
Phone: (843) 805-6888
Village Library
9 a.m. – 6 p.m.
Phone: (843) 884-9741
St. Paul's/Hollywood Library
9 a.m. – 8 p.m.
Phone: (843) 889-3300
Otranto Road Library
9 a.m. – 8 p.m.
Phone: (843) 572-4094
Mt. Pleasant Library
9 a.m. – 8 p.m.
Phone: (843) 849-6161
McClellanville Library
9 a.m. - 6 p.m.
Phone: (843) 887-3699
Keith Summey North Charleston Library
9 a.m. – 8 p.m.
Phone: (843) 744-2489
John's Island Library
9 a.m. – 8 p.m.
Phone: (843) 559-1945
Hurd/St. Andrews Library
9 a.m. – 8 p.m.
Phone: (843) 766-2546
Miss Jane's Building (Edisto Library Temporary Location)
9 a.m. – 6 p.m.
Phone: (843) 869-2355
Dorchester Road Library
9 a.m. – 8 p.m.
Phone: (843) 552-6466
John L. Dart Library
9 a.m. – 7 p.m.
Phone: (843) 722-7550
Baxter-Patrick James Island
9 a.m. – 8 p.m.
Phone: (843) 795-6679
Main Library
9 a.m. – 8 p.m.
Phone: (843) 805-6930
Bees Ferry West Ashley Library
9 a.m. – 8 p.m.
Phone: (843) 805-6892
Mobile Library
9 a.m. - 5 p.m.
Phone: (843) 805-6909
Today's Hours
West Ashley Library
9 a.m. – 7 p.m.
Phone: (843) 766-6635
Folly Beach Library
Closed
Phone: (843) 588-2001
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
Wando Mount Pleasant Library
9 a.m. – 8 p.m.
Phone: (843) 805-6888
Village Library
9 a.m. – 6 p.m.
Phone: (843) 884-9741
St. Paul's/Hollywood Library
9 a.m. – 8 p.m.
Phone: (843) 889-3300
Otranto Road Library
9 a.m. – 8 p.m.
Phone: (843) 572-4094
Mt. Pleasant Library
9 a.m. – 8 p.m.
Phone: (843) 849-6161
McClellanville Library
9 a.m. - 6 p.m.
Phone: (843) 887-3699
Keith Summey North Charleston Library
9 a.m. – 8 p.m.
Phone: (843) 744-2489
John's Island Library
9 a.m. – 8 p.m.
Phone: (843) 559-1945
Hurd/St. Andrews Library
9 a.m. – 8 p.m.
Phone: (843) 766-2546
Miss Jane's Building (Edisto Library Temporary Location)
9 a.m. – 6 p.m.
Phone: (843) 869-2355
Dorchester Road Library
9 a.m. – 8 p.m.
Phone: (843) 552-6466
John L. Dart Library
9 a.m. – 7 p.m.
Phone: (843) 722-7550
Baxter-Patrick James Island
9 a.m. – 8 p.m.
Phone: (843) 795-6679
Main Library
9 a.m. – 8 p.m.
Phone: (843) 805-6930
Bees Ferry West Ashley Library
9 a.m. – 8 p.m.
Phone: (843) 805-6892
Mobile Library
9 a.m. - 5 p.m.
Phone: (843) 805-6909
Patron Login
menu
Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
Extravascular lung water index improves the diagnostic accuracy of lung injury in patients with shock.
Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
- Author(s): Chew MS;Chew MS; Ihrman L; During J; Bergenzaun L; Ersson A; Undén J; Ryden J; Åkerman E; Larsson M
- Source:
Critical care (London, England) [Crit Care] 2012 Jan 03; Vol. 16 (1), pp. R1. Date of Electronic Publication: 2012 Jan 03.- Publication Type:
Journal Article; Research Support, Non-U.S. Gov't- Language:
English - Source:
- Additional Information
- Source: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 9801902 Publication Model: Electronic Cited Medium: Internet ISSN: 1466-609X (Electronic) Linking ISSN: 13648535 NLM ISO Abbreviation: Crit Care Subsets: MEDLINE
- Publication Information: Publication: London, UK : BioMed Central Ltd
Original Publication: London : Current Science Ltd, c1997- - Subject Terms:
- Abstract: Introduction: The diagnosis of acute lung injury (ALI) may be more robust if more accurate physiological markers can be identified. Extravascular lung water (EVLW) is one possible marker, and it has been shown to correlate with respiratory function and mortality in patients with sepsis. Whether EVLW confers diagnostic value in a general population with shock, as well as which index performs best, is unclear. We investigated the diagnostic accuracy of various EVLW indices in patients with shock.
Methods: We studied a prospective, observational cohort of 51 patients with shock admitted to a tertiary ICU. EVLW was measured within 6 hours of ICU admission and indexed to actual body weight (EVLW/ABW), predicted body weight (EVLW/PBW) and pulmonary blood volume (EVLW/PBV). The relationship of these indices to the diagnosis and severity of lung injury and ICU mortality were studied. Positive and negative likelihood ratios, pre- and posttest odds for diagnosis of lung injury and mortality were calculated.
Results: All EVLW indices were higher among patients with lung injury and significantly correlated with respiratory parameters. Furthermore, all EVLW indices were significantly higher in nonsurvivors. The use of EVLW improves the posttest OR for the diagnosis of ALI, acute respiratory distress syndrome (ARDS) and severe lung injury (sLI) by up to eightfold. Combining increased EVLW and a diagnosis of ALI, ARDS or sLI increases the posttest odds of ICU mortality. EVLW/ABW and EVLW/PBV demonstrated the best diagnostic performance in this population.
Conclusions: EVLW was associated with degree of lung injury and mortality, regardless of the index used, confirming that it may be used as a bedside indicator of disease severity. The use of EVLW as a bedside test conferred added diagnostic value for the identification of patients with lung injury. - Comments: Comment in: Crit Care. 2012;16(1):114. (PMID: 22369761)
Comment in: Crit Care. 2012;16(2):417. (PMID: 22424187)
Comment in: Crit Care. 2012;16(2):420; author reply 420. (PMID: 22494634) - References: Crit Care Med. 2006 Jun;34(6):1647-53. (PMID: 16625129)
Thorax. 2002 May;57(5):452-8. (PMID: 11978926)
Crit Care Med. 2008 Jun;36(6):1970. (PMID: 18520658)
Am J Physiol Lung Cell Mol Physiol. 2006 Dec;291(6):L1118-31. (PMID: 16891389)
Am Rev Respir Dis. 1988 Sep;138(3):720-3. (PMID: 3202424)
Anaesthesia. 2007 May;62(5):492-503. (PMID: 17448063)
Ann Surg. 1985 Dec;202(6):685-93. (PMID: 4073980)
Am J Respir Crit Care Med. 1994 Mar;149(3 Pt 1):818-24. (PMID: 7509706)
Crit Care Med. 2005 Nov;33(11):2547-54. (PMID: 16276179)
J Crit Care. 2010 Mar;25(1):16-22. (PMID: 19427761)
Am Rev Respir Dis. 1987 Sep;136(3):662-8. (PMID: 3307570)
Crit Care Med. 2008 Jan;36(1):69-73. (PMID: 18090369)
N Engl J Med. 2001 Mar 8;344(10):699-709. (PMID: 11236773)
Crit Care Med. 2008 Jun;36(6):1803-9. (PMID: 18496374)
Crit Care Med. 1998 Nov;26(11):1793-800. (PMID: 9824069)
Chest. 2002 Dec;122(6):2080-6. (PMID: 12475851)
Intensive Care Med. 2006 Sep;32(9):1315-21. (PMID: 16741694)
Chest. 1992 Jun;101(6):1644-55. (PMID: 1303622)
Intensive Care Med. 2007 Mar;33(3):400-2. (PMID: 17221188)
Crit Care Med. 2006 Mar;34(3):738-44. (PMID: 16521268)
Crit Care Med. 2004 Mar;32(3):858-73. (PMID: 15090974)
Am J Respir Crit Care Med. 2007 Oct 15;176(8):795-804. (PMID: 17585106)
Crit Care. 2005 Apr;9(2):R74-82. (PMID: 15774053)
BMJ. 2004 Jul 17;329(7458):168-9. (PMID: 15258077)
Intensive Care Med. 2007 Mar;33(3):448-53. (PMID: 17221189)
Respir Med. 2008 Jul;102(7):956-61. (PMID: 18397821)
Intensive Care Med. 2000 Feb;26(2):180-7. (PMID: 10784306)
Crit Care Med. 2010 Jan;38(1):114-20. (PMID: 19789451) - Publication Date: Date Created: 20120105 Date Completed: 20130611 Latest Revision: 20220310
- Publication Date: 20231215
- Accession Number: PMC3396226
- Accession Number: 10.1186/cc10599
- Accession Number: 22214612
- Source:
Contact CCPL
Copyright 2022 Charleston County Public Library Powered By EBSCO Stacks 3.3.0 [350.3] | Staff Login
No Comments.