The radiobiological and physical basis for radiotherapy with protons and heavier ions.

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  • Author(s): Kraft G;Kraft G
  • Source:
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] [Strahlenther Onkol] 1990 Jan; Vol. 166 (1), pp. 10-3.
  • Publication Type:
    Comparative Study; Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Urban & Vogel Country of Publication: Germany NLM ID: 8603469 Publication Model: Print Cited Medium: Print ISSN: 0179-7158 (Print) Linking ISSN: 01797158 NLM ISO Abbreviation: Strahlenther Onkol Subsets: MEDLINE
    • Publication Information:
      Original Publication: [München] : Urban & Vogel, [c1986-
    • Subject Terms:
      Ions* ; Physics* ; Protons* ; Radiobiology*; Neoplasms/*radiotherapy; Cell Cycle/radiation effects ; Dose-Response Relationship, Radiation ; Energy Transfer ; Humans ; Neoplasms/pathology ; Physical Phenomena ; Radiotherapy Dosage ; Radiotherapy, High-Energy ; Relative Biological Effectiveness ; Tumor Cells, Cultured
    • Abstract:
      Heavy charged particles exhibit a superior dose distribution compared to all conventionally used beams. The small lateral and range straggling, combined with an increase of the dose deposition with increasing penetration depth enables the production of dose profiles shaped precisely to the contours of the treatment volume. In addition, heavy ion beams exhibit an elevated biological efficiency close to the end of the particle range. Therefore, beams of heavy ions deliver a high physical dose combined with a high biological efficiency to a tumor volume while the surrounding healthy tissue is maximally spared.
    • Contributed Indexing:
      Indexing Agency: NASA Local ID #: 90141329.
    • Accession Number:
      0 (Ions)
      0 (Protons)
    • Publication Date:
      Date Created: 19900101 Date Completed: 19900309 Latest Revision: 20081121
    • Publication Date:
      20221208
    • Accession Number:
      2154042