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Evaluation of specific metabolic rates of major organs and tissues: comparison between men and women.
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- Author(s): Wang Z;Wang Z; Ying Z; Bosy-Westphal A; Zhang J; Heller M; Later W; Heymsfield SB; Müller MJ
- Source:
American journal of human biology : the official journal of the Human Biology Council [Am J Hum Biol] 2011 May-Jun; Vol. 23 (3), pp. 333-8. Date of Electronic Publication: 2010 Dec 22.
- Publication Type:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- Language:
English
- Additional Information
- Source:
Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8915029 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6300 (Electronic) Linking ISSN: 10420533 NLM ISO Abbreviation: Am J Hum Biol Subsets: MEDLINE
- Publication Information:
Publication: New York, NY : Wiley-Blackwell
Original Publication: New York, NY : Alan R. Liss, Inc., c1989-
- Subject Terms:
- Abstract:
Objectives: The specific resting metabolic rates (K(i) , in kcal/kg per day) of major organs and tissues in the Reference Man were suggested in 1992 by Elia: 200 for liver, 240 for brain, 440 for heart and kidneys, 13 for skeletal muscle, 4.5 for adipose tissue and 12 for the residual mass. However, it is unknown whether gender influences the K(i) values. The aim of the present study was to compare the K(i) values observed in nonelderly nonobese men to the corresponding values in women.
Methods: Elia's K(i) values were evaluated based on a mechanistic model: REE = Σ(K(i) × T(i) ), where REE is whole-body resting energy expenditure measured by indirect calorimetry and T(i) is the mass of major organs and tissues measured by magnetic resonance imaging. Marginal 95% confidence intervals (CIs) for the model-estimated K(i) values were calculated by stepwise univariate regression analysis. Subjects were nonelderly (age 20-49 years) nonobese (BMI 18.5-29.9 kg/m(2) ) men (n = 49) and women (n = 57).
Results: The measured REE (REEm) and the mass of major organs and skeletal muscle were all greater in the men than in women. The predicted REE by Elia's K(i) values were correlated with REEm in men (r = 0.87) and women (r = 0.86, both P < 0.001). Elia's K(i) values were within the range of 95% CIs for both men and women groups, revealing that gender adjustment is not necessary.
Conclusions: Elia's proposed adult K(i) values are valid in both nonelderly nonobese men and women. Further studies are needed to explore the potential influences of age and obesity on K(i) values in humans.
(Copyright © 2010 Wiley-Liss, Inc.)
- References:
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- Grant Information:
DK081633 United States DK NIDDK NIH HHS; R21 DK081633-02 United States DK NIDDK NIH HHS; R21 DK081633-01A1 United States DK NIDDK NIH HHS; R21 DK081633 United States DK NIDDK NIH HHS; P30 DK026687 United States DK NIDDK NIH HHS; P30 DK026687-31 United States DK NIDDK NIH HHS
- Publication Date:
Date Created: 20110413 Date Completed: 20110808 Latest Revision: 20220506
- Publication Date:
20240829
- Accession Number:
PMC3139779
- Accession Number:
10.1002/ajhb.21137
- Accession Number:
21484913
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