[Metformin as the first line antidiabetic agent].

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  • Author(s): Svacina S;Svacina S
  • Source:
    Vnitrni lekarstvi [Vnitr Lek] 2010 Dec; Vol. 56 (12), pp. 1225-7.
  • Publication Type:
    English Abstract; Journal Article; Review
  • Language:
    Czech
  • Additional Information
    • Transliterated Title:
      Postavení metforminu jako antidiabetika první volby.
    • Source:
      Publisher: Ambit Media Country of Publication: Czech Republic NLM ID: 0413602 Publication Model: Print Cited Medium: Print ISSN: 0042-773X (Print) Linking ISSN: 0042773X NLM ISO Abbreviation: Vnitr Lek Subsets: MEDLINE
    • Publication Information:
      Publication: 2010- : Brno : Ambit Media
      Original Publication: 1973-<1994> : Praha : Avicenum
    • Subject Terms:
      Diabetes Mellitus, Type 2/*drug therapy ; Hypoglycemic Agents/*therapeutic use ; Metformin/*therapeutic use ; Prediabetic State/*drug therapy; Animals ; Humans
    • Abstract:
      Metformin is considered to be the only drug suitable in patients with prediabetes and is the drug of choice in patients with type 2 diabetes. Apart from important antidiabetic effect, it also has some important additional effects: reduced incidence of tumours, positive effects on cardiovascular system, stimulation of immunity, positive effects on the bone, effect on ovulation, influence over body weight reduction, pancreas-protective effects (reduced incidence of carcinoma and possible effect on reduction in incidence of pancreatitis during incretin treatment), positive effects on liver steatosis. Since diabetes patients live with increased cardiovascular risk, it is important to continuously remind ourselves of the positive cardiovascular effects of metformin.
    • Accession Number:
      0 (Hypoglycemic Agents)
      9100L32L2N (Metformin)
    • Publication Date:
      Date Created: 20110126 Date Completed: 20110512 Latest Revision: 20131121
    • Publication Date:
      20221213
    • Accession Number:
      21261109