[A case of liver metastases from rectal cancer showed a complete response by FOLFIRI and bevacizumab chemotherapy].

Publisher: Gan To Kagaku Ryohosha Country of Publication: Japan NLM ID: 7810034 Publication Model: Print Cited Medium: Print ISSN: 0385-0684 (Print) Linking ISSN: 03850684 NLM ISO Abbreviation: Gan To Kagaku Ryoho Subsets: MEDLINE

Publication: Tokyo : Gan To Kagaku Ryohosha
Original Publication: Tōkyō, Gan to Kagaku Ryōhōsha [1974?]-

Angiogenesis Inhibitors/*administration & dosage ; Antibodies, Monoclonal/*administration & dosage ; Antineoplastic Combined Chemotherapy Protocols/*administration & dosage ; Liver Neoplasms/*drug therapy ; Liver Neoplasms/*secondary ; Rectal Neoplasms/*pathology; Antibodies, Monoclonal, Humanized ; Bevacizumab ; Camptothecin/administration & dosage ; Camptothecin/analogs & derivatives ; Fluorouracil/administration & dosage ; Humans ; Leucovorin/administration & dosage ; Male ; Middle Aged ; Treatment Outcome

A 62-year-old man had undergone anterior resection of rectum for rectosigmoid colon cancer with liver metastases. Postoperatively, the FOLOFOX6 regimen was performed in three courses. Metastatic liver tumors showed progressive disease(PD) on CT scan. The treatment was then changed to the FOLFIRI regimen for three courses. Metastatic liver tumors showed a partial response(PR)on CT scan. After six courses of the FOLFIRI regimen, the patient was given seven courses of the FOLFIRI +BV regimen. Hepatic resection of S2, S3, S4 and S6 segment was performed. The histological effect of chemotherapy was complete response(CR).

0 (Angiogenesis Inhibitors)
0 (Antibodies, Monoclonal)
0 (Antibodies, Monoclonal, Humanized)
2S9ZZM9Q9V (Bevacizumab)
Q573I9DVLP (Leucovorin)
U3P01618RT (Fluorouracil)
XT3Z54Z28A (Camptothecin)

IFL protocol

Date Created: 20101217 Date Completed: 20110125 Latest Revision: 20151119

20221213

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