Development of collateral circulation after acute myocardial infarction: its role in preserving left ventricular function.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8804703 Publication Model: Print Cited Medium: Print ISSN: 0914-5087 (Print) Linking ISSN: 09145087 NLM ISO Abbreviation: J Cardiol Subsets: MEDLINE
    • Publication Information:
      Publication: Amsterdam : Elsevier
      Original Publication: Tokyo : Japanese College Of Cardiology
    • Subject Terms:
      Ventricular Function, Left*; Coronary Circulation/*physiology ; Myocardial Infarction/*physiopathology; Adult ; Aged ; Chronic Disease ; Collateral Circulation/physiology ; Female ; Heart Ventricles/diagnostic imaging ; Humans ; Male ; Middle Aged ; Myocardial Contraction ; Myocardial Infarction/diagnostic imaging ; Radiography ; Stroke Volume
    • Abstract:
      The present study evaluated the effects of coronary collateral circulation developing after acute myocardial infarction on global and regional left ventricular function during the chronic stage. The study group consisted of 16 patients with initial myocardial infarction having total occlusion of the proximal left anterior descending coronary artery. To eliminate the effects of collateral circulation existing at the onset of infarction, patients with pre-infarction angina were excluded from this study. The patients were categorized in two groups depending on the extent of their collateral circulation (collateral index: CI 0-3): group A--patients with significant collateral circulation (CI = 2 or 3) to the infarct-related coronary artery; group B--patients without significant collateral circulation (CI = 0 or 1). Their heart rate, left ventricular peak systolic and end-diastolic pressures and cardiac index were similar in the two groups. The left ventricular end-systolic volume index in the group B was significantly greater than that in the group A (60 +/- 21 ml/m2 vs 34 +/- 9 ml/m2, p less than 0.05). Left ventricular ejection fraction in the group A was significantly greater than that of the group B (55 +/- 9% vs 39 +/- 15%, p less than 0.05), and a significant difference was observed in the percentage of segment shortening in the infarct area between the groups A and B (10.8 +/- 9.2% vs -0.2 +/- 5.4%, p less than 0.01). It was concluded that coronary collateral circulation which develops after acute myocardial infarction exerts beneficial effects on global and regional left ventricular function during the chronic stage.
    • Publication Date:
      Date Created: 19900101 Date Completed: 19910626 Latest Revision: 20161123
    • Publication Date:
      20221208
    • Accession Number:
      2093759