Can super-antibody drugs be tamed?

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    • Subject Terms:
      LONDON (England); ENGLAND
    • Abstract:
      The article reports that the clinical trial for experimental antibody drug TGN1412 put six male volunteers at London, England's Northwick Park Hospital intensive care. The British Medical and Healthcare products Regulatory Agency has ruled out any failure of experimental and regulatory procedures. The volunteers were probably struck by a flood of inflammatory molecules released by helper T cells, which shut down their organs in hours.