A comparative study of the biological properties of Australian elapid venoms.

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  • Author(s): Tan NH;Tan NH; Ponnudurai G
  • Source:
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology [Comp Biochem Physiol C Comp Pharmacol Toxicol] 1990; Vol. 97 (1), pp. 99-106.
  • Publication Type:
    Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Elsevier Science Country of Publication: England NLM ID: 8310013 Publication Model: Print Cited Medium: Print ISSN: 0742-8413 (Print) Linking ISSN: 07428413 NLM ISO Abbreviation: Comp Biochem Physiol C Comp Pharmacol Toxicol Subsets: MEDLINE
    • Publication Information:
      Publication: Oxford : Elsevier Science
      Original Publication: Oxford ; New York : Pergamon Press, c1983-c1993.
    • Subject Terms:
      Elapid Venoms/*toxicity; Animals ; Australia ; Chromatography, Gel ; Elapid Venoms/isolation & purification ; Elapid Venoms/metabolism ; Elapid Venoms/pharmacology ; Hydrolases/isolation & purification ; Hydrolases/metabolism ; Snakes ; Species Specificity
    • Abstract:
      1. The hemorrhagic, procoagulant, anticoagulant, protease, phosphodiesterase, alkaline phosphomonoesterase, L-amino acid oxidase, acetylcholinesterase, arginine ester hydrolase, phospholipase A, 5'-nucleotidase and hyaluronidase activities of 39 samples of venoms from 13 species (15 taxa) of Australian elapids were determined and the Sephadex G-75 gel filtration patterns for some of the venoms were also examined. 2. The results indicate that Australian elapid venoms can be divided into two groups: procoagulant Australian venoms (including N. scutatus, N. ater, O. scutellatus, O. microlepidotus, P. porphyriacus, T. carinatus, H. stephensii and P. textilis) and non-procoagulant Australian venoms (including A. superbus, P. colletti, P. australis, P. guttatus and A. antarcticus). 3. The non-procoagulant Australian venoms exhibited biological properties similar to other elapid venoms, while the procoagulant Australian venoms exhibited some properties characteristic of viperid venoms. 4. The data show that information on venom biological properties can be used for differentiation of many species of Australian elapids. 5. Particularly useful for this purpose are the hyaluronidase, alkaline phosphomonoesterase, acetylcholinesterase, and the procoagulant activities and the Sephadex G-75 gel filtration patterns of the venoms.
    • Accession Number:
      0 (Elapid Venoms)
      EC 3.- (Hydrolases)
    • Publication Date:
      Date Created: 19900101 Date Completed: 19910409 Latest Revision: 20200825
    • Publication Date:
      20221208
    • Accession Number:
      10.1016/0742-8413(90)90178-c
    • Accession Number:
      1981349