An unusual cause of haemoptysis and headache: cryptococcosis.

Publisher: Academy of Medicine of Malyasia, College of Pathologists Country of Publication: Malaysia NLM ID: 8101177 Publication Model: Print Cited Medium: Print ISSN: 0126-8635 (Print) Linking ISSN: 01268635 NLM ISO Abbreviation: Malays J Pathol Subsets: MEDLINE

Publication: June 2000- : Kuala Lumpur : Academy of Medicine of Malyasia, College of Pathologists
Original Publication: Kuala Lumpur : Malaysian Society of Pathologists.

Cryptococcosis/*pathology ; Headache/*etiology ; Hemoptysis/*etiology ; Lung Diseases, Fungal/*pathology; Adult ; Amphotericin B/therapeutic use ; Antifungal Agents/therapeutic use ; Cryptococcosis/complications ; Cryptococcosis/drug therapy ; Diagnosis, Differential ; Fluconazole/therapeutic use ; Humans ; Lung Diseases, Fungal/complications ; Lung Diseases, Fungal/drug therapy ; Lung Neoplasms/pathology ; Recurrence

Pulmonary cryptococcosis can be clinically silent in non-HIV infected patients but can also present as nodules and masses on the chest radiograph, which can be mistaken for tuberculosis or lung cancer. Common symptoms include fever and cough, and uncommonly haemoptysis. This report illustrates a non-HIV infected patient whose main complaint was haemoptysis and headache. He was diagnosed with pulmonary cryptococcosis from biopsy of an endobronchial mass found on flexible bronchoscopy. Disseminated cryptoccoccal infection should be considered as a differential diagnosis in non-HIV infected patients presenting with haemoptysis and headache. Early recognition and administration of appropriate therapy will improve clinical outcome in these patients.

0 (Antifungal Agents)
7XU7A7DROE (Amphotericin B)
8VZV102JFY (Fluconazole)

Date Created: 20090319 Date Completed: 20090430 Latest Revision: 20131121

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