[Development of novel biomaterials for bone and cartilage tissue engineering].

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  • Author(s): Kawazoe N;Kawazoe N; Chen G; Tateishi T
  • Source:
    Clinical calcium [Clin Calcium] 2008 Dec; Vol. 18 (12), pp. 1713-20.
  • Publication Type:
    Journal Article; Review
  • Language:
    Japanese
  • Additional Information
    • Source:
      Publisher: Iyaku (Medicine & Drug) Journal Co., Ltd Country of Publication: Japan NLM ID: 9433326 Publication Model: Print Cited Medium: Print ISSN: 0917-5857 (Print) Linking ISSN: 09175857 NLM ISO Abbreviation: Clin Calcium Subsets: MEDLINE
    • Publication Information:
      Publication: Ōsaka-shi : Iyaku (Medicine & Drug) Journal Co., Ltd
      Original Publication: Ōsaka-shi : Iyaku Jānarusha,
    • Subject Terms:
      Biocompatible Materials* ; Bone and Bones* ; Cartilage* ; Regenerative Medicine* ; Tissue Engineering* ; Tissue Scaffolds*; Animals ; Bone Regeneration ; Chondrocytes ; Collagen ; Humans ; Lactic Acid ; Polyglycolic Acid ; Polylactic Acid-Polyglycolic Acid Copolymer ; Polymers ; Porosity
    • Abstract:
      Three-dimensional porous scaffolds play an important role in cartilage and bone tissue engineering as temporary templates for transplanted cells to control their adhesion and proliferation to guide the formation of the new tissues. The scaffolds should be biodegradable, biocompatible, mechanically strong, and capable of being formed into desired shapes. Biodegradable synthetic polymers and naturally derived collagen have their respective advantages and drawbacks. Hybridization of the two kinds of polymers has been carried out to combine their respective advantages. This review will summarize some of the recently developed porous scaffolds having hybrid, biphasic and leakproof structures, and their application to bone and cartilage tissue engineering.
    • Number of References:
      14
    • Accession Number:
      0 (Biocompatible Materials)
      0 (Polymers)
      1SIA8062RS (Polylactic Acid-Polyglycolic Acid Copolymer)
      26009-03-0 (Polyglycolic Acid)
      33X04XA5AT (Lactic Acid)
      9007-34-5 (Collagen)
    • Publication Date:
      Date Created: 20081202 Date Completed: 20090206 Latest Revision: 20181201
    • Publication Date:
      20221213
    • Accession Number:
      CliCa081217131720
    • Accession Number:
      19043184