[Advances of cell transplantation for treating intervertebral disc degeneration].

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  • Author(s): Liu J;Liu J; Wang J
  • Source:
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery [Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi] 2008 Oct; Vol. 22 (10), pp. 1259-63.
  • Publication Type:
    English Abstract; Journal Article; Review
  • Language:
    Chinese
  • Additional Information
    • Source:
      Publisher: Hua xi yi ke da xue Fu shu di 1 yi yuan Country of Publication: China NLM ID: 9425194 Publication Model: Print Cited Medium: Print ISSN: 1002-1892 (Print) Linking ISSN: 10021892 NLM ISO Abbreviation: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi Subsets: MEDLINE
    • Publication Information:
      Publication: Chengdu Shi : Hua xi yi ke da xue Fu shu di 1 yi yuan
      Original Publication: Chengdu Shi : Hua xi yi ke da xue Fu shu di 1 yi yuan,
    • Subject Terms:
      Cell Transplantation* ; Intervertebral Disc*/pathology; Spinal Diseases/*surgery
    • Abstract:
      Objective: To introduce the research of cell transplantation for treating intervertebral disc degeneration.
      Methods: The original articles in recent years about cell transplantation for treating intervertebral disc degeneration were extensively reviewed, and retrospective and comprehensive analysis was performed.
      Results: Transplantation of intervertebral disc-derived cells or BMSCs by pure cell transplantation or combined with collagen scaffold into intervertebral disc could express nucleus pulposus-like phenotype. All the cells transplanted into intervertebral disc could increase extracellular matrix synthesis and relieve or even inhibit further intervertebral disc degeneration.
      Conclusion: Cell transplantation for treating intervertebral disc degeneration may be a promising approach.
    • Number of References:
      41
    • Publication Date:
      Date Created: 20081105 Date Completed: 20090612 Latest Revision: 20111117
    • Publication Date:
      20231215
    • Accession Number:
      18979891