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[Protein kinases C: a new cytoplasmic target].
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- Additional Information
- Transliterated Title:
Protéines kinases C : une nouvelle cible cytoplasmique.
- Source:
Publisher: Elsevier Country of Publication: France NLM ID: 0072416 Publication Model: Print Cited Medium: Internet ISSN: 1769-6917 (Electronic) Linking ISSN: 00074551 NLM ISO Abbreviation: Bull Cancer Subsets: MEDLINE
- Publication Information:
Publication: Jan. 2015- : Paris : Elsevier
Original Publication: Paris : Masson
- Subject Terms:
- Abstract:
Protein kinase C (PKC) are cytoplasmic serine-threonine kinases, analysis of their involvement in oncogenesis is complex. Deregulated expressions of certain PKC can be observed in various tumors, but there is great variability in the roles of these enzymes according isoform or cell type (pro- or anti-proliferative action). Although understanding of the role of PKC in tumor development is still incomplete, different agents are currently evaluated. This review discusses the available data, with special emphasis on clinical outcomes.
- Number of References:
91
- Accession Number:
0 (Indoles)
0 (Isoenzymes)
0 (Neoplasm Proteins)
0 (Phosphorothioate Oligonucleotides)
0 (Protein Kinase Inhibitors)
EC 2.7.11.13 (Protein Kinase C)
FMT95051CQ (aprinocarsen)
H88EPA0A3N (Staurosporine)
ID912S5VON (midostaurin)
UC96G28EQF (enzastaurin)
- Publication Date:
Date Created: 20080830 Date Completed: 20080905 Latest Revision: 20161124
- Publication Date:
20221213
- Accession Number:
10.1684/bdc.2008.0665
- Accession Number:
18755647
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