[Methodological aspects of evaluation of potential lipid capacity for peroxidation from the serum levels of TBA-active products during iron ion stimulation].

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  • Additional Information
    • Source:
      Publisher: Meditsina Country of Publication: Russia (Federation) NLM ID: 9432021 Publication Model: Print Cited Medium: Print ISSN: 0869-2084 (Print) Linking ISSN: 08692084 NLM ISO Abbreviation: Klin Lab Diagn Subsets: MEDLINE
    • Publication Information:
      Original Publication: Moskva : "Meditsina", 1992-
    • Subject Terms:
      Lipid Peroxidation* ; Oxidative Stress*; Iron/*blood ; Thiobarbituric Acid Reactive Substances/*analysis; Blood Chemical Analysis ; Ions/blood ; Ions/chemistry ; Iron/chemistry ; Lipoproteins, HDL/blood ; Lipoproteins, HDL/chemistry ; Lipoproteins, VLDL/blood ; Lipoproteins, VLDL/chemistry ; Thiobarbituric Acid Reactive Substances/chemistry
    • Abstract:
      The authors propose a simple and reproducible procedure for using iron ions to stimulate serum lipid peroxidation, with TBA-active products being further determined. The procedure determines the reserve of lipids that can be oxidized during oxidative stress. A combination of direct studies and correlation analysis suggests that low-density lipoproteins and very low-density lipoproteins are the major substrates for lipid peroxidation while high-density lipoproteins show a high resistance to this process. The presented procedure may be used to monitor lipid peroxidation in various conditions and upon various exposures in common laboratory practice.
    • Accession Number:
      0 (Ions)
      0 (Lipoproteins, HDL)
      0 (Lipoproteins, VLDL)
      0 (Thiobarbituric Acid Reactive Substances)
      E1UOL152H7 (Iron)
    • Publication Date:
      Date Created: 20080702 Date Completed: 20080722 Latest Revision: 20190816
    • Publication Date:
      20240829
    • Accession Number:
      18590162