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Painful tongue ulcerations in patients with bisphosphonate-associated osteonecrosis of the jaws.
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- Author(s): Treister NS;Treister NS; Richardson P; Schlossman R; Miller K; Woo SB
- Source:
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics [Oral Surg Oral Med Oral Pathol Oral Radiol Endod] 2008 Jun; Vol. 105 (6), pp. e1-4. Date of Electronic Publication: 2008 Apr 16.
- Publication Type:
Case Reports; Journal Article
- Language:
English
- Additional Information
- Source:
Publisher: Elsevier Country of Publication: United States NLM ID: 9508562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-395X (Electronic) Linking ISSN: 10792104 NLM ISO Abbreviation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod Subsets: MEDLINE
- Publication Information:
Publication: 2004- : St. Louis, MO : Elsevier
Original Publication: St. Louis, MO : Mosby-Year Book, Inc., c1995-
- Subject Terms:
- Abstract:
Objectives: Bisphosphonate-associated osteonecrosis of the jaws (BONJ) is a recently recognized and well described complication in cancer patients. While pain and associated morbidity have been reported, this has largely been attributed to localized infection of the nonvital bone and surrounding soft tissue, or in rare cases, pathologic fracture.
Study Design: Cancer patients who were treated with intravenous bisphosphonate therapy and subsequently developed BONJ with associated traumatic tongue ulcerations were reported.
Results: We report a series of 5 patients who presented with unilateral painful tongue ulcerations secondary to the tongue rubbing against adjacent exposed mylohyoid bone on the lingual surface of the mandible. Smoothing, recontouring, or removal of the bone, and in some cases intralesional steroid therapy, resulted in complete resolution of symptoms.
Conclusions: Oral health care specialists and physicians must be alert to this potential complication of BONJ because it is easily managed with conservative measures and results in rapid and significant improvement in symptoms and overall quality of life.
- Accession Number:
0 (Bone Density Conservation Agents)
0 (Diphosphonates)
0 (Glucocorticoids)
F446C597KA (Triamcinolone Acetonide)
- Publication Date:
Date Created: 20080418 Date Completed: 20080630 Latest Revision: 20131121
- Publication Date:
20250114
- Accession Number:
10.1016/j.tripleo.2008.02.010
- Accession Number:
18417376
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