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Triggering receptors expressed on myeloid cells in pulmonary aspiration syndromes.
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- Author(s): El Solh AA;El Solh AA; Akinnusi ME; Peter M; Berim I; Schultz MJ; Pineda L
- Source:
Intensive care medicine [Intensive Care Med] 2008 Jun; Vol. 34 (6), pp. 1012-9. Date of Electronic Publication: 2008 Apr 08.- Publication Type:
Journal Article- Language:
English - Source:
- Additional Information
- Source: Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0342-4642 (Print) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE
- Publication Information: Publication: New York : Springer Verlag
Original Publication: Berlin ; New York, Springer International. - Subject Terms: Biomarkers/*metabolism ; Membrane Glycoproteins/*metabolism ; Myeloid Cells/*metabolism ; Pneumonia/*diagnosis ; Pneumonia, Aspiration/*diagnosis ; Receptors, Immunologic/*metabolism; Bronchoalveolar Lavage Fluid/chemistry ; Bronchoalveolar Lavage Fluid/cytology ; Case-Control Studies ; Chi-Square Distribution ; Diagnosis, Differential ; Female ; Humans ; Male ; Middle Aged ; Pneumonia/metabolism ; Pneumonia/microbiology ; Pneumonia, Aspiration/metabolism ; Pneumonia, Aspiration/microbiology ; Prospective Studies ; ROC Curve ; Respiration, Artificial ; Statistics, Nonparametric ; Triggering Receptor Expressed on Myeloid Cells-1
- Abstract: Objective: To investigate the potential role of serum and alveolar soluble triggering receptor expressed on myeloid cells (sTREM-1) as a biological marker of pulmonary aspiration syndromes.
Design: Prospective cohort study.
Setting: University-affiliated intensive care unit.
Patients: Seventy-five patients with pulmonary aspiration and 13 controls receiving mechanical ventilation.
Interventions: Blood and bronchoalveolar lavage (BAL) fluid samples were collected on enrollment. Soluble TREM-1 levels were measured by an enzyme-linked immunosorbent assay.
Measurements and Results: Thirty-eight of 75 participants had documented BAL culture-positive pulmonary aspiration. While circulating levels of sTREM-1 were comparable between those with aspiration syndromes (19.81 +/- 12.09 pg/ml) and controls (15.96 +/- 11.16 pg/ml) (p=0.27), the alveolar levels of sTREM-1 were higher in patients with culture-positive pulmonary aspiration (344.41 +/- 152.82 pg/ml) compared with those culture-negative pulmonary aspiration (142.76 +/- 89.88 pg/ml; p < 0.001). A cut-off value of 250 pg/ml for alveolar sTREM-1 achieved a sensitivity of 65.8% (95% CI 48.6-80.4) and a specificity of 91.9% (95% CI 78.1-98.2) with an area under the curve of 0.87 (95% CI 0.78-0.94).
Conclusions: Alveolar sTREM-1 levels can be a potential biomarker for distinguishing BAL culture-positive from BAL culture-negative pulmonary aspiration. - Comments: Comment in: Intensive Care Med. 2008 Jun;34(6):981-4. (PMID: 18392806)
- References: Ann Intern Med. 2004 Jul 6;141(1):9-15. (PMID: 15238365)
Scand J Clin Lab Invest. 1997 Apr;57(2):111-8. (PMID: 9200269)
J Chronic Dis. 1987;40(5):373-83. (PMID: 3558716)
Crit Care Med. 1985 Oct;13(10):818-29. (PMID: 3928249)
Nature. 2001 Apr 26;410(6832):1103-7. (PMID: 11323674)
Pediatr Pulmonol. 1999 Jun;27(6):419-22. (PMID: 10380094)
Crit Care Med. 2005 Apr;33(4):792-6. (PMID: 15818107)
J Am Geriatr Soc. 2003 Jan;51(1):17-23. (PMID: 12534840)
Radiology. 1982 Apr;143(1):29-36. (PMID: 7063747)
Chest. 1998 Mar;113(3 Suppl):228S-232S. (PMID: 9515898)
Eur Respir J. 2004 Aug;24(2):247-50. (PMID: 15332392)
Eur J Immunol. 2001 Mar;31(3):783-91. (PMID: 11241283)
Intensive Care Med. 2005 Nov;31(11):1495-500. (PMID: 16195904)
N Engl J Med. 2004 Jan 29;350(5):451-8. (PMID: 14749453)
J Am Geriatr Soc. 2005 May;53(5):755-61. (PMID: 15877549)
Intensive Care Med. 2006 Jan;32(1):110-5. (PMID: 16284739)
J Immunol. 2000 May 15;164(10):4991-5. (PMID: 10799849)
N Engl J Med. 2001 Mar 1;344(9):665-71. (PMID: 11228282) - Accession Number: 0 (Biomarkers)
0 (Membrane Glycoproteins)
0 (Receptors, Immunologic)
0 (TREM1 protein, human)
0 (Triggering Receptor Expressed on Myeloid Cells-1) - Publication Date: Date Created: 20080409 Date Completed: 20090108 Latest Revision: 20211020
- Publication Date: 20231215
- Accession Number: 10.1007/s00134-008-1087-7
- Accession Number: 18392807
- Source:
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