Metabolic complications of childhood obesity: identifying and mitigating the risk.

Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE

Publication: Alexandria Va : American Diabetes Association
Original Publication: New York, American Diabetes Assn.

Obesity/*complications; Adolescent ; Child ; Ethnicity/statistics & numerical data ; Fatty Liver/epidemiology ; Female ; Glucose/metabolism ; Glucose Intolerance/epidemiology ; Glucose Intolerance/etiology ; Humans ; Insulin Resistance ; Life Style ; Lipids/physiology ; Obesity/epidemiology ; Obesity/genetics ; Obesity/prevention & control ; Pregnancy ; Racial Groups/statistics & numerical data ; Risk Factors ; Risk Reduction Behavior ; United States/epidemiology

The growing number of obese children and adolescents across the world creates a diagnostic challenge to caregivers. The early clinical manifestations of abnormalities related to childhood obesity, attributed to obesity-driven insulin resistance, are impaired glucose metabolism and nonalcoholic fatty liver disease. Both have no symptoms and demand a high index of suspicion and the proper choice of tests for establishing the diagnosis. The clinician should gather information derived from thoroughly taken history and a focused physical examination to stratify patients by their risk. Focused lifestyle modification-aimed interventions are showing promising results in improving the metabolic profile of obese children. Early diagnosis may help allocate resources for intensive interventions that may benefit individuals at greatest risk for early obesity-related morbidity.

77

0 (Lipids)
IY9XDZ35W2 (Glucose)

Date Created: 20080215 Date Completed: 20080328 Latest Revision: 20220317

20240628

10.2337/dc08-s273

18227502