The Glutamatergic Projection from the Substantia Nigra Pars Reticulata to the Dorsal Raphe Nucleus Facilitates Social Hierarchy in Mice.

The article discusses the role of glutamatergic neurons in the substantia nigra pars reticulata (SNr) in establishing and maintaining social hierarchy in mice. The study found that activating these neurons increased during effortful behaviors and could influence social rank through connections with the dorsal raphe nucleus (DRN). Additionally, activating SNr glutamatergic terminals in the DRN reduced anxiety levels in mice. This research enhances understanding of the functions of SNr glutamatergic neurons in both normal contexts and neurological disorders. [Extracted from the article]

Copyright of Health & Medicine Week is the property of NewsRx and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)