Molecular testing and precision oncology: An overview.

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    • Subject Terms:
      TUMOR diagnosis; TUMOR genetics; GENOMICS; MOLECULAR probes; ANTINEOPLASTIC agents; ONCOLOGY; TUMOR markers; DNA probes; METASTASIS; CANCER chemotherapy; TUMORS; INDIVIDUALIZED medicine; GENETIC mutation; MOLECULAR diagnosis; MOLECULAR pathology; SEQUENCE analysis; GENETIC testing; PHARMACODYNAMICS
    • Abstract:
      Targeted therapy has emerged as a promising option in cancer treatment, driven by advances in the understanding of DNA changes and the molecular basis of cancer. This article provides an overview of next-generation sequencing and types of genetic alterations, common cancer biomarkers, a review of circulating tumor DNA testing and its applications for oncology treatments, how to read a genomic testing report, examples of targeted therapy for cancer pathologic variants and tumor markers, and the implications for nursing practice in this emerging field. This article provides an overview of next-generation sequencing and types of genetic alterations, common cancer biomarkers, a review of circulating tumor DNA testing and its applications for oncology treatments, how to read a genomic testing report, examples of targeted therapy for cancer pathologic variants and tumor markers, and the implications for nursing practice. [ABSTRACT FROM AUTHOR]
    • Abstract:
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