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Detecting carcinoembryonic antigen based on the aggregation-induced emission enhancement effect.
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- Author(s): Lu, Yanjun; Wang, Mengqi; Yang, Yiwen; Tang, Qiukai; Zeng, Yanbo; Wang, Hailong; Zhang, Lijie; Pan, Chengrui; Hu, Changkun; Fu, Zhuowei; Li, Lei
- Source:
Chemical Communications; 11/28/2024, Vol. 60 Issue 92, p13570-13573, 4p
- Subject Terms:
- Additional Information
- Abstract:
In this study, a novel label-free fluorescent aptasensor with an aggregation-induced emission enhancement effect was developed and applied for the detection of carcinoembryonic antigen (CEA). The sensor has a simple detection mechanism, easy operation, high sensitivity (with low limit of detection of 1 pg mL−1), good selectivity, and wide linear range (0.003–10 ng mL−1). In addition, it can be directly applied for the determination of CEA in human serum. [ABSTRACT FROM AUTHOR]
- Abstract:
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