The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation.

The article discusses a study on the HIV-1 virus and the role of the conserved spacer peptide 2 (SP2) in triggering matrix lattice maturation, leading to the formation of infectious virions. The research reveals that SP2 binds to the membrane binding domain MA, inducing structural maturation and faster fusion of the virus with target cells. This study provides new insights into the interaction between HIV-1 components and sheds light on the mechanism of MA lattice maturation. [Extracted from the article]

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