The landscape of RNA binding proteins in mammalian spermatogenesis.

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    • Subject Terms:
      RNA-binding proteins; SPERMATOGENESIS; MALE infertility
    • Abstract:
      The article focuses on the role of ribonucleic acid (RNA) binding proteins (RBPs) in mammalian spermatogenesis and their connection to male infertility. Topics discussed include the identification and characterization of RBPs in mouse male germ cells (mMGCs), the discovery of the glutamic acid-arginine (ER) patch as a significant enhancer of RNA binding, and the implications of RBPs for understanding the genetic architecture of male infertility.