Reports from Fuzhou University Provide New Insights into Nanoparticles (Bismuth Tungstate-based Nanoparticles Promoting Healing of Drug-resistant Bacteria Infected Abscesses By Chemical/low-temperature Photothermal Therapy).

Researchers from Fuzhou University in China have developed polyhexamethylene biguanide-bismuth tungstate-poly(vinylpyrrolidone) nanoparticles (PHMB-BWO-PVP NPs) for the treatment of drug-resistant bacterial infections. These nanoparticles combine chemical and low-temperature photothermal therapy (CT/LT-PTT) to effectively combat multidrug-resistant infections. The NPs were found to have excellent bactericidal effects against drug-resistant bacteria and inhibited the formation of bacterial biofilms. In addition, the NPs promoted wound tissue healing by inducing the transformation of macrophages and facilitating collagen deposition and angiogenesis. This research provides new insights into the use of nanoparticles for the treatment of drug-resistant bacterial infections. [Extracted from the article]

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