Exploiting the mechanical effects of ultrasound for noninvasive therapy.

HIGH-intensity focused ultrasound; TARGETED drug delivery; IMMUNE checkpoint inhibitors; IMMUNOLOGICAL adjuvants; CENTRAL nervous system

Focused ultrasound (FUS) is a versatile medical technology that uses sound waves to generate therapeutic effects without damaging surrounding tissue. It can be used in various ways, such as thermal ablation for destroying growths or nonthermal mechanisms for more subtle effects. The next generation of ultrasound-mediated therapies is currently being developed, with applications in cancer, neurodegenerative disease, cardiovascular health, and more. Research is particularly focused on the brain, where ultrasound is being used to enable targeted drug delivery and neuromodulation. The field of ultrasound therapy is growing, with increased availability of clinical systems and ongoing clinical trials to test efficacy. [Extracted from the article]

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