First People's Hospital Reports Findings in Brain Injury (The Effect of Riboflavin on Neurological Rehabilitation after Traumatic Brain Injury in Children).

A study conducted at the First People's Hospital in Zhejiang, China, explored the effects of riboflavin (RF) on neurological rehabilitation and functional recovery after traumatic brain injury (TBI) in children. The study used rat models of TBI and investigated the impact of RF on sensorimotor function, cognitive ability, lesion volume, water content, neural apoptosis, neuroinflammation, oxidative stress, angiogenesis, and vascular remodeling. The administration of RF was found to facilitate the recovery of neurological function, reduce lesion volume and water content, ameliorate neural apoptosis, neuroinflammation, and oxidative stress, and promote angiogenesis. These findings provide a novel mechanism for RF in treating pediatric TBI. [Extracted from the article]

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