Yan'an University Reports Findings in Parkinson's Disease (Antinociceptive Role of the Thalamic Dopamine D3 Receptor In Descending Modulation of Intramuscular Formalin-induced Muscle Nociception In a Rat Model of Parkinson's Disease).

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    • Abstract:
      A study conducted by researchers at Yan'an University in China explores the role of the dopamine D3 receptor in the modulation of pain in Parkinson's disease (PD). The study found that PD rats exhibited increased muscle nociception compared to control rats, and the activation of dopamine D3 receptors in the thalamic mediodorsal (MD) and ventromedial (VM) nuclei attenuated pain responses. The findings suggest that dopamine D3 receptors in the thalamus play an antinociceptive role in the descending modulation of pain in PD. This research was supported by the National Natural Science Foundation of China. [Extracted from the article]
    • Abstract:
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