行脊柱手术患者围手术期内静脉血栓的预防策略及应用效果. (Chinese)

Prevention strategy of venous thrombosis in patients undergoing spinal surgery during perioperative period and its application effect. (English)

Objective To analyze the prevention strategy of venous thrombosis in patients undergoing spinal surgery during perioperative period and its application effect. Methods A total of 110 patients undergoing spinal surgery admitted to Nanfang Hospital of Southern Medical University from June 2020 to June 2022 were included in the study. The observation group (55 cases) and the control group (55 cases) were included by simple randomization method. Both groups received routine perioperative nursing, while the observation group additionally received evidence-based nursing for venous thrombosis prevention. The coagulation function and other indexes of the two groups were compared. Results On the 3rd day after surgery, the plasma prothrombin time (PT), activated partial thromboplastin time (APTT) and thrombin time (TT) in both groups were shorter than those on the 1st day before surgery, but those indexes in the observation group were longer than those in the control group. On the 7th day after surgery, the TT of the observation group was shorter than that on the 1st day before surgery, and PT, APTT and TT in the control group were shorter than those on the 1st day before surgery and those in the observation group, with statistical differences (all P < 0. 05). The plasma fibrinogen and D-dimer levels in both groups on the 3rd and 7th day after surgery were higher than those on the 1st day before surgery, but those indexes in the observation group were lower than those in the control group at the same period (all P < 0. 05). On the 3rd day after surgery, the blood flow velocity of common femoral vein, popliteal vein and iliac vein in both groups was slower than that on the 1st day before surgery, but the index in the observation group was faster than that in the control group. On the 7th day after surgery, the blood flow velocity of the common femoral vein and iliac vein in the observation group was slower than that on the 1st day before surgery, while the blood flow velocity of the common femoral vein, popliteal vein and iliac vein in the control group was slower than that on the 1st day before surgery and in the same period of the observation group, with statistical differences (all P < 0. 05). The incidence of venous thrombosis in the observation group was lower than that in the control group (P < 0. 05 ). Conclusion The prevention strategy of perioperative venous thrombosis in patients undergoing spinal surgery based on evidence-based evidence can effectively improve the fluctuation of blood flow velocity, coagulation function and related indexes of patients, and reduce the incidence of venous thrombosis. [ABSTRACT FROM AUTHOR]

目的 分析行脊柱手术患者围手术期内的静脉血栓预防策略及应用效果. 方法 纳入南方医科大学南方医 院于 2020 年 6 月至 2022 年 6 月收治的 110 例行脊柱手术患者进行研究, 使用简单随机法分别将其纳入观察组 (55 例) 和对照组 (55 例). 2 组均接受常规围手术期护理, 观察组加用针对静脉血栓预防的循证护理. 对比 2 组的 凝血功能等指标. 结果 术后 3 d, 2 组的血浆凝血酶原时间 (PT), 活化部分凝血活酶时间 (APTT) 和凝血酶时间 (TT) 均较术前 1 d 更短, 但观察组均较对照组更长; 术后 7 d, 观察组的 TT 较术前 1 d 更短, 对照组的 PT, APTT, TT 均较术前 1 d 及观察组更短, 均有统计学差异 (P 均 < 0. 05). 2 组在术后 3 d 和 7 d 的血浆纤维蛋白原和 D-二聚体 水平均较术前 1 d 升高, 但观察组均低于同期对照组 (P 均 < 0. 05). 术后 3 d, 2 组的股总静脉, 腘静脉和髂静脉血 流速度均较术前 1 d 减慢, 但观察组均快于对照组; 术后 7 d, 观察组的股总静脉和髂静脉血流速度均较术前 1 d 更 慢, 对照组的股总静脉, 腘静脉和髂静脉血流速度均较术前 1 d 及同期观察组更慢, 均有统计学差异 (P 均 < 0. 05). 观察组的静脉血栓发生率较对照组更低 (P < 0. 05). 结论 基于循证证据建立的行脊柱手术患者围手术期内静脉 血栓预防策略能够有效改善患者的血流速度波动, 凝血功能及相关指标, 降低静脉血栓发生率。 [ABSTRACT FROM AUTHOR]

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