Research on Escherichia coli Published by a Researcher at Beijing University of Civil Engineering and Architecture [Formation mechanism of injured bacteria after disinfection with epigallocatechin gallate (EGCG) as a disinfectant].

A study conducted by researchers at Beijing University of Civil Engineering and Architecture explored the effects of epigallocatechin gallate (EGCG), the main antibacterial component of tea polyphenols, on Escherichia coli (E. coli) in terms of disinfection damage and the underlying mechanisms. The researchers found that different concentrations of EGCG resulted in damaged bacteria, with the extent of damage depending on the dosage and treatment duration. The disinfection process involving EGCG caused oxidative damage in E. coli, leading to alterations in the antioxidant system of the bacteria. E. coli responded to the oxidative stress by adjusting gene expression related to peroxidase and glutathione metabolism processes. These findings contribute to our understanding of tea polyphenols' disinfection effects and provide insights into EGCG's mechanisms of damaging bacteria such as E. coli. [Extracted from the article]

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