Advancing Early Diagnosis of Alzheimers Disease: A Paper-Based Aptasensor for Detecting Amyloid Beta(1-42) and p-tau181 from Plasma Using CdTe Quantum Dots.

A preprint abstract from biorxiv.org discusses the development of a paper-based aptasensor for the early detection of Alzheimer's Disease (AD). The sensor uses quantum dots (QDs) and Forster Resonance Energy Transfer (FRET) to target amyloid beta (1-42) and p-tau181 proteins, which are biomarkers for AD. The sensor shows a linear correlation between fluorescence quenching and protein concentration, and it holds promise for the early diagnosis of AD and personalized medicine. However, it is important to note that this preprint has not been peer-reviewed. [Extracted from the article]

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