Study Data from Queen Mary University of London Update Knowledge of Aquaporins (Efficient generation of a stable CHO-K1 cell line overexpressing the human water channel aquaporin-5 as tool to generate therapeutic antibodies).

A study conducted at Queen Mary University of London provides new information on aquaporins, which are water permeable channels expressed on the plasma membrane. The researchers aimed to generate a stable cell line that overexpresses the human water channel aquaporin-5 (AQP5) in order to develop potential recombinant antibodies targeting AQP5. The study found that the new cell line can also be used to study the molecular mechanisms of AQP5 sub-cellular trafficking. This research is relevant to the field of immunology and may have implications for the treatment of conditions such as Sjogren's syndrome. [Extracted from the article]

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