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Sex Differences in Autism Heritability and Likelihood: What's in a Residual?
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- Author(s): Tsompanidis, Alex; Warrier, Varun; Baron-Cohen, Simon
- Source:
JAMA Psychiatry; Jul2024, Vol. 81 Issue 7, p643-644, 2p- Subject Terms:
- Source:
- Additional Information
- Abstract: This editorial discusses the heritability and likelihood of autism, focusing on the differences between males and females. The authors highlight that autism is a neurodevelopmental condition with a wide range of behaviors and cognitive skills. They discuss a study that found higher heritability for autism in males compared to females, contradicting the idea of a "female protective effect." The authors suggest that the differences in heritability may be due to greater genetic variability in males. They also mention the importance of considering neurodiversity and the impact of gene-environment interactions, particularly during prenatal development. The study's findings warrant further research and consideration of factors such as intellectual disability, age of diagnosis, and prenatal hormone levels. [Extracted from the article]
- Abstract: Copyright of JAMA Psychiatry is the property of American Medical Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
- Abstract:
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